01 / NAICS Market Profile
NAICS 325414 Biological Product (Except Diagnostic) Manufacturing Federal Contracts
North American Industry Classification System code 325414
Federal contract activity classified under Biological Product (Except Diagnostic) Manufacturing across FY 2020–FY 2026. Net obligations include both new obligations and subsequent deobligations.
02 / Market Size
How large is the NAICS 325414 federal market?
03 / Spending Trend
NAICS 325414 contract spending by fiscal year
Annual obligations, activity, and participation across the same FY 2020–FY 2026 profile window.
| Fiscal year | Obligations | Actions | Vendors | Customers | Change |
|---|---|---|---|---|---|
| FY 2020 | $1.49B | 984 | 260 | 27 | — |
| FY 2021 | $19.76B | 1,009 | 263 | 21 | +1,222.9% |
| FY 2022 | $2.49B | 1,040 | 247 | 24 | −87.4% |
| FY 2023 | $209.66M | 858 | 218 | 23 | −91.6% |
| FY 2024 | $989.95M | 815 | 214 | 24 | +372.2% |
| FY 2025 | -$52.05M | 539 | 156 | 24 | −105.3% |
| FY 2026 | $457.82M | 367 | 129 | 20 | +979.5% |
04 / Top Federal Customers
Which federal agencies buy most in this industry?
Ranked by net obligations during FY 2020–FY 2026.
| Federal customer | Code | Obligations | Actions | Vendors | Market share |
|---|---|---|---|---|---|
| DEPT OF THE ARMY | 2100 | $20.83B | 164 | 29 | 82.2% |
| ADMINISTRATION FOR STRATEGIC PREPAREDNESS AND RESPONSE | 7505 | $3.82B | 423 | 37 | 15.1% |
| DEFENSE LOGISTICS AGENCY | 97AS | $326.51M | 353 | 27 | 1.3% |
| ANIMAL AND PLANT HEALTH INSPECTION SERVICE | 12K3 | $165.46M | 138 | 26 | 0.7% |
| NATIONAL INSTITUTES OF HEALTH | 7529 | $91.21M | 3,081 | 387 | 0.4% |
| VETERANS AFFAIRS, DEPARTMENT OF | 3600 | $61.76M | 459 | 40 | 0.2% |
| DEFENSE HEALTH AGENCY (DHA) | 97DH | $19.74M | 127 | 19 | 0.1% |
| FOOD AND DRUG ADMINISTRATION | 7524 | $10.86M | 173 | 31 | 0.0% |
| CENTERS FOR DISEASE CONTROL AND PREVENTION | 7523 | $7.03M | 239 | 64 | 0.0% |
| FOOD SAFETY AND INSPECTION SERVICE | 12G2 | $4.61M | 90 | 6 | 0.0% |
05 / Contracting Offices
Which contracting offices buy in NAICS 325414?
Ranked by net obligations during FY 2020–FY 2026.
| Office | Code | Agency | Obligations | Actions | Vendors | Market share |
|---|---|---|---|---|---|---|
| W6QK ACC-PICA | W15QKN | DEPT OF THE ARMY | $13.74B | 33 | 2 | 54.2% |
| W6QK ACC-APG NATICK | W58P05 | DEPT OF THE ARMY | $7.09B | 28 | 2 | 28.0% |
| BARDA - ASPR / DAAPPO / BARDA DCMA | 75A501 | ADMINISTRATION FOR STRATEGIC PREPAREDNESS AND RESPONSE | $3.17B | 405 | 37 | 12.5% |
| ASPR/ORM-SNS | 75A503 | OFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSE | $341.95M | 12 | 2 | 1.3% |
| DLA TROOP SUPPORT | SPE2DP | DEFENSE LOGISTICS AGENCY | $324.87M | 130 | 9 | 1.3% |
| INDUSTRIAL BASED MANUFACTURING AND SUPPLY CHAIN (IBMSC) | 75A504 | ADMINISTRATION FOR STRATEGIC PREPAREDNESS AND RESPONSE | $309.50M | 6 | 1 | 1.2% |
| MRPBS MINNEAPOLIS MN | 126395 | ANIMAL AND PLANT HEALTH INSPECTION SERVICE | $164.93M | 125 | 21 | 0.7% |
| NATIONAL INSTITUTES OF HEALTH NIAID | 75N930 | NATIONAL INSTITUTES OF HEALTH | $35.51M | 1,131 | 171 | 0.1% |
| 256-NETWORK CONTRACT OFFICE 16 (36C256) | 36C256 | VETERANS AFFAIRS, DEPARTMENT OF | $19.00M | 97 | 8 | 0.1% |
| 252-NETWORK CONTRACT OFFICE 12 (36C252) | 36C252 | VETERANS AFFAIRS, DEPARTMENT OF | $17.25M | 193 | 6 | 0.1% |
06 / Top Vendors
Which contractors lead the NAICS 325414 market?
| Vendor | Obligations | Actions | Customers | Market share | Latest activity |
|---|---|---|---|---|---|
| PFIZER INC. | $15.26B | 60 | 2 | 60.2% | Mar 11, 2025 |
| REGENERON PHARMACEUTICALS, INC. | $5.57B | 8 | 1 | 21.9% | Jul 29, 2022 |
| MODERNATX, INC. | $1.75B | 24 | 1 | 6.9% | Apr 10, 2025 |
| ADVANCED TECHNOLOGY INTERNATIONAL | $911.50M | 55 | 1 | 3.6% | Aug 19, 2026 |
| EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. | $687.65M | 15 | 1 | 2.7% | Jun 26, 2026 |
| VALNEVA USA, INC. | $161.93M | 21 | 1 | 0.6% | Sep 5, 2024 |
| SEQIRUS INC. | $135.14M | 70 | 1 | 0.5% | Sep 29, 2026 |
| MERCK SHARP & DOHME CORP. | $102.30M | 8 | 2 | 0.4% | Jun 28, 2024 |
| RETRACTABLE TECHNOLOGIES, INC. | $93.79M | 10 | 1 | 0.4% | Apr 18, 2022 |
| SANOFI PASTEUR INC. | $82.57M | 137 | 7 | 0.3% | Apr 8, 2026 |
07 / Product and Service Mix
What products and services are purchased under NAICS 325414?
| PSC | Description | Obligations | Actions | Vendors | Share |
|---|---|---|---|---|---|
| 6505 | DRUGS AND BIOLOGICALS | $21.58B | 2,524 | 335 | 85.1% |
| AN11 | HEALTH R&D SERVICES; HEALTH CARE SERVICES; BASIC RESEARCH | $1.76B | 50 | 9 | 6.9% |
| 6515 | MEDICAL AND SURGICAL INSTRUMENTS, EQUIPMENT, AND SUPPLIES | $911.98M | 290 | 52 | 3.6% |
| AN42 | HEALTH R&D SERVICES; HEALTH CARE - OTHER; APPLIED RESEARCH | $909.74M | 57 | 3 | 3.6% |
| Z2EC | REPAIR OR ALTERATION OF PRODUCTION BUILDINGS | $102.30M | 5 | 1 | 0.4% |
| Q999 | MEDICAL- OTHER | $55.58M | 11 | 3 | 0.2% |
| 6550 | IN VITRO DIAGNOSTIC SUBSTANCES, REAGENTS, TEST KITS AND SETS | $35.21M | 672 | 96 | 0.1% |
| AN12 | HEALTH R&D SERVICES; HEALTH CARE SERVICES; APPLIED RESEARCH | $33.65M | 12 | 3 | 0.1% |
| 6509 | DRUGS AND BIOLOGICALS, VETERINARY USE | $25.25M | 323 | 90 | 0.1% |
| 6640 | LABORATORY EQUIPMENT AND SUPPLIES | $21.78M | 711 | 153 | 0.1% |
08 / Buying Pattern
How does the government buy in NAICS 325414?
| Common action type | Obligations | Actions |
|---|---|---|
| PURCHASE ORDER | $103.04M | 3,488 |
| DELIVERY ORDER | $1.83B | 1,200 |
| BPA CALL | $9.69M | 660 |
| DEFINITIVE CONTRACT | $23.42B | 264 |
09 / Recent Contract Awards
What was awarded most recently in NAICS 325414?
10 / Market Interpretation
How should contractors evaluate this market?
Start with the spending direction
Compare annual obligations with actions and vendor participation. Growth driven by only a few large actions represents a different opportunity from broad, recurring demand.
Follow the actual buyers
Move from federal customers to contracting offices. Offices reveal where acquisition responsibility and recurring purchasing activity are concentrated.
Measure accessible demand
Use competition, small-business participation, incumbent vendors, and PSC mix before treating the full $25.36B market as addressable.